在植物中工程化生产次生代谢产物。

Engineering secondary metabolite production in plants.

作者信息

Verpoorte R, Memelink J

机构信息

Division of Pharmacognosy, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands.

出版信息

Curr Opin Biotechnol. 2002 Apr;13(2):181-7. doi: 10.1016/s0958-1669(02)00308-7.

DOI:10.1016/s0958-1669(02)00308-7

PMID:11950573

Abstract

Recent achievements have been made in the metabolic engineering of plant secondary metabolism. Various pathways have been altered using genes encoding biosynthetic enzymes or genes encoding regulatory proteins. In addition, antisense genes have been used to block competitive pathways, thereby increasing the flux towards the desired secondary metabolites.

摘要

植物次生代谢的代谢工程最近取得了一些成果。利用编码生物合成酶的基因或编码调控蛋白的基因改变了各种途径。此外，反义基因已被用于阻断竞争途径，从而增加通往所需次生代谢产物的通量。