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[磁共振胆胰管造影术在胆总管结石快速诊断中的价值]

[The value of magnetic resonance cholangiography for the expedient diagnosis of choledocholithiasis].

作者信息

Mussack Thomas, Ladurner R, Rock C, Trupka A, Gross M

机构信息

Chirurgische Klinik und Poliklinik--Innenstadt, Germany.

出版信息

Dtsch Med Wochenschr. 2002 Apr 12;127(15):786-90. doi: 10.1055/s-2002-25020.

Abstract

INTRODUCTION

Management of symptomatic cholecystolithiasis is vitally influenced by dilated biliary tract and choledocholithiasis. The objectives of this prospective pilot study were to evaluate the diagnostic value of preoperative magnetic resonance cholangiography (MRC) compared to diagnostic endoscopic retrograde cholangiography (ERC) and to establish an efficient algorithm for diagnostics and treatment of choledocholithiasis.

METHODS

All consecutive patients with cholecystolithiasis and dilated biliary tract proven by sonography as well as elevated liver function tests were enrolled within 12 months. Patients without evidence of bile duct calculi underwent preoperative MRC, whereas patients with choledocholithiasis immediate ERC.

RESULTS

58 patients (30 male, 28 female) with a median age of 59.4 years underwent preoperative MRC. In 18 patients (10 male, 8 female; median age 63.5 years) with evidence of choledocholithiasis we subsequently performed ERC and papillotomy. Bile duct stones were detected and removed after papillotomy in 10 patients, whereas calculi could not be found anymore in 8 patients. The remaining 40 patients without calculi evident on MRC were transferred to magnetic resonance tomography and ERC in case of suspected malignancy or to cholecystectomy and intraoperative cholangiography (IOC), which could definitely exclude choledocholithiasis. In comparison to ERC respectively IOC, MRC was able to detect bile duct stones with a sensitivity of 100% and a specificity of 83.3%.

CONCLUSIONS

Non-invasive MRC seems to replace diagnostic ERC concerning the presence of choledocholithiasis in case of cholecystolithiasis and dilated biliary tract with a high sensitivity. The preoperative ERC with stone extraction is still the therapy of choice in case of radiologically confirmed choledocholithiasis.

摘要

引言

有症状的胆囊结石的治疗受到胆道扩张和胆总管结石的重大影响。本前瞻性初步研究的目的是评估术前磁共振胆胰管造影(MRC)与诊断性内镜逆行胆胰管造影(ERC)相比的诊断价值,并建立一种胆总管结石诊断和治疗的有效算法。

方法

在12个月内纳入所有经超声证实有胆囊结石和胆道扩张以及肝功能检查升高的连续患者。无胆管结石证据的患者接受术前MRC,而有胆总管结石的患者立即进行ERC。

结果

58例患者(男性30例,女性28例),中位年龄59.4岁,接受了术前MRC。在18例有胆总管结石证据的患者(男性10例,女性8例;中位年龄63.5岁)中,我们随后进行了ERC和乳头切开术。10例患者在乳头切开术后检测并取出了胆管结石,而8例患者未再发现结石。其余40例MRC未发现结石证据的患者,如怀疑有恶性肿瘤则转至磁共振断层扫描和ERC,或转至胆囊切除术和术中胆管造影(IOC),后者可明确排除胆总管结石。与ERC或IOC相比,MRC检测胆管结石的敏感性为100%,特异性为83.3%。

结论

对于胆囊结石合并胆道扩张且存在胆总管结石的情况,非侵入性MRC似乎可以以高敏感性取代诊断性ERC。对于经放射学证实的胆总管结石,术前ERC取石仍是首选治疗方法。

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