Horie Y, Akamizu H, Nishimura Y, Maeda N, Kawasaki H, Kimura O, Hirooka Y, Hamazoe R, Kaibara N, Ohta Y
2nd Department of Internal Medicine, Tottori University School of Medicine.
Hepatogastroenterology. 1995 Sep-Oct;42(5):506-9.
The prognosis of primary liver cancer, especially cholangiocarcinoma, is extremely poor. A long term, 12 years survivor of intrahepatic cholangiocarcinoma arising in a local dilatation of the intrahepatic bile duct is presented. A 40-year-old male patient was presented with recurrent upper abdominal pain, fever, and jaundice. Computed tomography revealed a localized duct dilatation, and ultrasound clearly demonstrated a tumor mass arising within the bile duct. At surgery in March, 1982, the tumor mass was resected and histologically confirmed as a well differentiated papillary adenocarcinoma arising. In March, 1994, the patient is alive and cancer-free, 12 years after surgical resection. To our knowledge, there has been no report on a patient surviving more than 10 years after initial treatment. This case suggests that a localized cystic dilatation of the intrahepatic-bile duct on imaging modalities may harbor a bile duct carcinoma, and this in turn may contribute to early diagnosis of carcinomas and improved long term survival.
原发性肝癌，尤其是胆管癌的预后极差。本文报告了一例肝内胆管局部扩张引发的肝内胆管癌患者存活达12年的长期病例。一名40岁男性患者出现反复上腹部疼痛、发热和黄疸症状。计算机断层扫描显示局部胆管扩张，超声检查清晰显示胆管内有肿瘤肿块。1982年3月手术时，切除了肿瘤肿块，组织学检查确诊为高分化乳头状腺癌。1994年3月，患者在手术切除12年后仍然存活且无癌。据我们所知，此前尚无关于患者初始治疗后存活超过10年的报道。该病例表明，影像学检查发现的肝内胆管局限性囊性扩张可能隐藏胆管癌，这反过来可能有助于癌症的早期诊断并提高长期生存率。
