Savage E W
J Reprod Med. 1975 Dec;15(6):211-3.
This study describes 50 patients with abnormal cervical Papanicolaou smears who had colposcopically directed biopsies and then subsequent cervical conization. The objective was to test the accuracy of directed biopsies compared with that of standard method of diagnosis. A significant difference between the two methods occurred in 4% of patients. This figure is the same as that gained from a review of current literature (3.8%). There were no invasive carcinomas in this series.
本研究描述了50例宫颈巴氏涂片异常的患者，这些患者接受了阴道镜引导下活检，随后进行了宫颈锥切术。目的是测试引导活检与标准诊断方法相比的准确性。两种方法在4%的患者中存在显著差异。该数字与对当前文献回顾得出的结果相同（3.8%）。本系列中无浸润性癌。
