Muncaster A, Lewis H M
Department of Dermatology, Selly Oak Hospital, University Hospital Birmingham NHS Trust, Birmingham.
Clin Exp Dermatol. 2002 Jan;27(1):24-6. doi: 10.1046/j.0307-6938.2001.00945.x.
Linear IgA disease (LAD) is a well recognized subepidermal blistering disorder characterized by linear deposits of IgA at the basement membrane zone. The aetiology is unknown but there is a recognized association with lymphoproliferative malignancies. We report a case of LAD occurring in a patient with multicentric Castleman's disease (angiofollicular lymph node hyperplasia), an association not previously recorded in the literature.
线状IgA大疱性皮肤病(LAD)是一种公认的表皮下大疱性疾病,其特征为IgA在基底膜带呈线状沉积。病因不明,但已知与淋巴增生性恶性肿瘤有关。我们报告1例LAD发生于多中心Castleman病(血管滤泡性淋巴结增生症)患者,这种关联此前文献中未见记载。