Petersen V C, Underwood J C E, Wells M, Shepherd N A
Department of Histopathology, Gloucestershire Royal Hospital, Gloucester, UK.
Histopathology. 2002 Feb;40(2):171-6. doi: 10.1046/j.1365-2559.2002.01313.x.
Three cases of endometrioid adenocarcinoma arising in colorectal endometriosis are described with discussion of their macroscopic and microscopic pathology and diagnosis, using immunohistochemistry.
Three middle-aged women presented with symptoms and signs of colorectal mass effect. Two had a preceding history of gynaecological endometriosis and all three had either been on hormone replacement therapy or had functioning ovaries prior to presentation with colorectal disease. Each underwent resection of tumours of the distal large intestine. The definitive diagnosis was dependent on histological examination and immunohistochemistry, which was used to demonstrate an origin in endometriotic tissue.
Endometrioid adenocarcinoma is a rare complication of colorectal endometriosis, this report contributing to a total of 25 cases in the literature. Definitive diagnosis, aided by immunohistochemical studies, is important to enable the identification of the optimal management for this uncommon condition.
描述3例发生于结直肠子宫内膜异位症的子宫内膜样腺癌病例，并探讨其大体和微观病理学特征及诊断，同时运用免疫组织化学方法。
3例中年女性表现出结直肠肿块效应的症状和体征。其中2例有妇科子宫内膜异位症病史，且3例在出现结直肠疾病之前均接受过激素替代治疗或有功能正常的卵巢。每位患者均接受了远端大肠肿瘤切除术。最终诊断依赖于组织学检查和免疫组织化学，后者用于证实肿瘤起源于子宫内膜异位组织。
子宫内膜样腺癌是结直肠子宫内膜异位症的一种罕见并发症，本报告使文献中该病例总数增至25例。借助免疫组织化学研究进行明确诊断，对于确定这种罕见病症的最佳治疗方案非常重要。
