Ozaki Toshifumi, Liljenqvist Ulf, Hillmann Axel, Halm Henry, Lindner Norbert, Gosheger Georg, Winkelmann Winfried
Department of Orthopaedics, Westfälische Wilhelms-University, Münster, Germany.
Clin Orthop Relat Res. 2002 Apr(397):394-402. doi: 10.1097/00003086-200204000-00046.
Osteoblastomas and osteoid osteomas of the spine are relatively rare bone-forming tumors. Between 1980 and 1999, nine patients with osteoid osteoma and 13 patients with osteoblastoma had surgery for their tumors. Four tumors were in the cervical spine, six tumors were in thoracic spine, 10 tumors were in the lumbar spine, and two tumors were in the sacrum. The average duration between onset of pain and surgery was 16.6 months in 12 patients treated in the 1980s and 8.6 months in 10 patients treated in the 1990s. Seventeen patients had scoliosis. In nine of 10 patients with magnetic resonance imaging scans, high signal intensity areas in the muscles and bone around the lesion were seen. Two of nine patients with osteoid osteoma and nine of 13 patients with osteoblastoma had neurologic disorders before treatment. All patients had open resection of the lesions. Two patients with osteoid osteoma had relapse because of incomplete resection, necessitating a second excision. In 16 of 17 patients with preoperative spinal deformity, the deformity improved during followup. With development of modern imaging techniques, exact surgical planning may become possible; however, in some cases, intraoperative complete resection of the lesion still is difficult.
脊柱骨母细胞瘤和骨样骨瘤是相对罕见的成骨性肿瘤。1980年至1999年间，9例骨样骨瘤患者和13例骨母细胞瘤患者接受了肿瘤手术。4个肿瘤位于颈椎，6个肿瘤位于胸椎，10个肿瘤位于腰椎，2个肿瘤位于骶骨。20世纪80年代接受治疗的12例患者中，疼痛发作至手术的平均时长为16.6个月，20世纪90年代接受治疗的10例患者中这一平均时长为8.6个月。17例患者患有脊柱侧弯。在接受磁共振成像扫描的10例患者中，有9例在病变周围的肌肉和骨骼中可见高信号强度区域。9例骨样骨瘤患者中有2例以及13例骨母细胞瘤患者中有9例在治疗前出现神经功能障碍。所有患者均接受了病变的开放性切除。2例骨样骨瘤患者因切除不完全而复发，需要再次切除。17例术前存在脊柱畸形的患者中，有16例在随访期间畸形有所改善。随着现代成像技术的发展，精确的手术规划或许成为可能；然而，在某些情况下，术中完全切除病变仍然困难。
