Floman Y, Milgrom C, Kenan S, Sabato S, Robin G C
Orthopedics. 1985 Dec;8(12):1478-84. doi: 10.3928/0147-7447-19851201-07.
Eleven cases of osteoblastoma (spongious osteoblastoma) and four cases of osteoid osteoma (cortical osteoblastoma) involving the spine, diagnosed at Hadassah Hospital between 1970 and 1983 were analyzed. The age range was 7 to 34 years and the average clinical follow up was 63 months. The cervical spine was involved in four patients, thoracic in four, lumbar in six and the sacrum in one patient. Back or neck pain associated with stiffness was present in all cases and was often accompanied by scoliosis or torticollis. All the patients with osteoid osteoma were symptom relieved by surgery without recurrence. Seven of the patients with benign osteoblastoma presented with neurological signs or symptoms and three of these had recurrence following primary surgery. Although cortical and spongious osteoblastoma are considered as members of the same family of benign tumors of osteoblastic derivation, spongious osteoblastoma does not seem to be limited in growth potential as is cortical osteoblastoma.
对1970年至1983年间在哈达萨医院诊断出的11例骨母细胞瘤（海绵状骨母细胞瘤）和4例骨样骨瘤（皮质骨母细胞瘤）累及脊柱的病例进行了分析。年龄范围为7至34岁，平均临床随访时间为63个月。4例患者颈椎受累，4例胸椎受累，6例腰椎受累，1例骶骨受累。所有病例均出现与僵硬相关的背部或颈部疼痛，常伴有脊柱侧凸或斜颈。所有骨样骨瘤患者术后症状缓解，无复发。7例良性骨母细胞瘤患者出现神经体征或症状，其中3例在初次手术后复发。虽然皮质骨母细胞瘤和海绵状骨母细胞瘤被认为是成骨细胞源性良性肿瘤家族的成员，但海绵状骨母细胞瘤的生长潜能似乎不像皮质骨母细胞瘤那样受到限制。
