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Postmortem revelation of sickle cell disease following fatal episode of acute bronchial asthma.

作者信息

de la Grandmaison G Lorin, Paraire F

机构信息

Department of Pathology and Forensic Medicine, Raymond Poincaré Hospital, University R. Descartes, Paris-Ouest, 104 Boulevard Raymond Poincaré, F-92380, Garches, France.

出版信息

Forensic Sci Int. 2002 Mar 28;126(1):48-52. doi: 10.1016/s0379-0738(02)00028-2.

DOI:10.1016/s0379-0738(02)00028-2
PMID:11955832
Abstract

A 19-year-old black male with previous history of mild bronchial asthma presented sudden dyspnea and died in a state of respiratory distress in spite of resuscitation attempts. Autopsy showed typical lesions of acute bronchial asthma in a context of long-standing asthma associated with a massive and disseminated intravascular sickling. Hemoglobin electrophoresis diagnosed heterozygous sickle cell disease. This rare case raises the problem of the accuracy of death certificate, especially the difficulties to distinguish postmortem lesions as the underlying cause of death or the contributory cause of death.

摘要

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