Añó M A, Maselli J P, Sanz M L, Fernández-Benítez M
Departamento de Alergología e Inmunología Clínica, Clínica Universitaria de Navarra, Universidad de Navarra, Pamplona, Spain.
Allergol Immunopathol (Madr). 2002 Mar-Apr;30(2):104-8. doi: 10.1016/s0301-0546(02)79099-x.
food allergy is highly prevalent in our environment, especially among atopic patients. Pinus pinea is common in our region and its fruit, the pine nut, is allergologically important. Several cases have been reported in the literature that demonstrate the existence of common antigenic bands between pine nut and almond. In this study we try to assess this finding and the possible existence of common allergens by in vitro techniques.
we present a 10-year-old boy, previously diagnosed of seasonal rhinoconjunctivitis with sensitisation to grass and olive pollen, who had an anaphylactic reaction after eating pine nut. We performed in vivo (prick test, prick-by-prick) and in vitro tests (total and specific IgE determinations [CAP-FEIA]), histamine release test, and immunoblotting (SDS-PAGE). We also reviewed the literature through the MEDLINE database in PubMed.
because pine nut is commonly consumed in our environment, the prevalence of allergic reactions is probably considerable and these reactions take place at an early age. We demonstrate the existence of common antigenic proteins between pine nut and peanuts.
食物过敏在我们所处的环境中非常普遍，尤其是在特应性患者中。意大利石松在我们地区很常见，其果实松子在过敏学上具有重要意义。文献中报道了几例病例，表明松子和杏仁之间存在共同的抗原条带。在本研究中，我们试图通过体外技术评估这一发现以及共同过敏原的可能存在情况。
我们报告一名10岁男孩，此前被诊断为对草和橄榄花粉过敏的季节性鼻结膜炎，在食用松子后发生过敏反应。我们进行了体内试验（点刺试验、逐点刺试验）和体外试验（总IgE和特异性IgE测定[CAP-FEIA]）、组胺释放试验和免疫印迹（SDS-PAGE）。我们还通过PubMed中的MEDLINE数据库查阅了文献。
由于松子在我们的环境中普遍食用，过敏反应的发生率可能相当高，且这些反应在早年就会发生。我们证明了松子和花生之间存在共同的抗原蛋白。
