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进餐频率对高脂饮食正常受试者昼夜脂质、葡萄糖和胰岛素水平的影响;与高碳水化合物饮食所得数据的比较。

Influence of meal frequency on diurnal lipid, glucose and insulin levels in normal subjects on a high fat diet; comparison with data obtained on a high carbohydrate diet.

作者信息

van Gent C M, Pagano Mirani-Oostdijk C, van Reine P H, Frölich M, Hessel L W, Terpstra J

出版信息

Eur J Clin Invest. 1979 Dec;9(6):443-6. doi: 10.1111/j.1365-2362.1979.tb00910.x.

DOI:10.1111/j.1365-2362.1979.tb00910.x
PMID:119642
Abstract

Diurnal levels of serum triglyceride (TG) were measured in six normal persons consuming a fixed solid 65% fat diet under steady state conditions in a metabolic unit. The food was divided into either three or eight similar portions, differently spaced over the day and night. The diurnal TG-profiles on this diet were practically identical to those found under comparable conditions on a 65% carbohydrate diet [1]. Mean diurnal TG values did not significantly differ with varying meal frequency. Free fatty acid levels, however, were significantly higher on a high fat diet. Post-prandial glucose and insulin reponses did not significantly differ whether a high fat diet or a high carbohydrate diet was consumed. We conclude that the composition of the diet is of little importance in determining diurnal TG patterns when the diet consists of normal food stuffs, but that these patterns are dependent on meal frequency and distribution.

摘要

在一个代谢单元中,对6名食用固定固体65%脂肪饮食的正常人在稳态条件下的血清甘油三酯(TG)日间水平进行了测量。食物被分成三份或八份相似的部分,在白天和晚上以不同的间隔时间进食。这种饮食的日间TG曲线与在类似条件下食用65%碳水化合物饮食时发现的曲线几乎相同[1]。平均日间TG值不会因进餐频率不同而有显著差异。然而,高脂肪饮食时游离脂肪酸水平显著更高。无论食用高脂肪饮食还是高碳水化合物饮食,餐后血糖和胰岛素反应均无显著差异。我们得出结论,当饮食由正常食物组成时,饮食成分在决定日间TG模式方面不太重要,但这些模式取决于进餐频率和分布。

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引用本文的文献

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Lack of suppression of circulating free fatty acids and hypercholesterolemia during weight loss on a high-fat, low-carbohydrate diet.在高脂肪、低碳水化合物饮食减肥期间,循环游离脂肪酸不受抑制和高胆固醇血症。
Am J Clin Nutr. 2010 Mar;91(3):578-85. doi: 10.3945/ajcn.2009.27909. Epub 2010 Jan 27.