Farbu Elisabeth, Gilhus Nils Erik
Departmentt of Neurology, Haukeland University Hospital, 5021 Bergen, Norway.
J Neurol. 2002 Apr;249(4):404-9. doi: 10.1007/s004150200030.
Eighty former poliomyelitis patients and the sibling nearest in age and of same sex were examined with matched-pair analysis to evaluate the effect of previous poliomyelitis (polio) on social factors and general health. Fifty-four pairs with women (68 %), and 26 pairs with men (32 %) with a mean age 60.4 years were included. Data were collected by questionnaire. There was no significant difference in length of education between patients and siblings (categories < 8 years, 8-12 years, and > 12 years). Employment rate at age 40 years was 78 % for patients and 88 % for siblings (full-time or part-time); this difference was not significant. Educational options were considered to have been excellent by 38 % of the patients and 26 % of the siblings (not significant), with a fair agreement within the pairs (kappa=0.31). There was no significant difference regarding professional options; rated as excellent by 33 % of patients, and 28 % of siblings, with a fair agreement (kappa=0.25) also for this issue. Perception of general health today expressed on a horizontal VAS-scale (0-10) was significantly lower among the patients than the siblings, mean values of 5.8 and 6.8 (P < 0.001) respectively. Patients also reported a lower quality of life (P=0.03), and less energy for leisure activities (P=0.008). Post polio symptoms like muscular and articular pain, and abnormal tiredness were more common among patients than siblings, whereas there was no difference regarding coexisting illness. In conclusion, polio patients and their siblings reckoned their educational and professional options to have been at the same level. The patients were well educated and employed to the same degree up to the age of 40 years, but now at a higher age reported reduced general health.
对80名曾患小儿麻痹症的患者以及年龄最相近且性别相同的兄弟姐妹进行了配对分析检查，以评估既往小儿麻痹症（脊髓灰质炎）对社会因素和总体健康的影响。研究纳入了54对女性（68%）和26对男性（32%），平均年龄为60.4岁。通过问卷调查收集数据。患者和其兄弟姐妹在受教育年限方面（分类为<8年、8 - 12年和>12年）没有显著差异。40岁时的就业率，患者为78%，兄弟姐妹为88%（全职或兼职）；该差异不显著。38%的患者和26%的兄弟姐妹认为教育选择非常好（无显著差异），配对组内有适度一致性（kappa = 0.31）。在职业选择方面也没有显著差异；33%的患者和28%的兄弟姐妹将其评为非常好，在这个问题上也有适度一致性（kappa = 0.25）。在水平视觉模拟量表（0 - 10）上，患者对当前总体健康的感知明显低于其兄弟姐妹，平均值分别为5.8和6.8（P < 0.001）。患者还报告生活质量较低（P = 0.03），休闲活动精力较少（P = 0.008）。脊髓灰质炎后症状如肌肉和关节疼痛以及异常疲劳在患者中比在其兄弟姐妹中更常见，而在并存疾病方面没有差异。总之，脊髓灰质炎患者及其兄弟姐妹认为他们的教育和职业选择处于同一水平。患者在40岁之前受教育程度和就业程度相同，但现在年龄较大时报告总体健康状况下降。
