Mignon F C, Laroche L, Revuz J, Chatel A, Cattan D, Bader J P
Nouv Presse Med. 1975 Oct 18;4(35):2507-10.
Two cases of acanthosis nigricans seen in 2 women, the characteristics of which were those of malignant forms, showed oesophageal involvment, the appearance of which was quite similar to that of the mucosal localisations of the syndrome. The authors discuss the features which distinguish the oesophageal localisation of acanthosis nigricans from other types of oesophageal acanthosis or papillomata. In one case, this type of acanthosis, seven years after its onset, was not associated with any detectable malignant change and in the other the cutaneous lesions were improved following surgery at which the associated gastric tumour was not removed.
两名女性患者出现黑棘皮病，其特征为恶性类型，均有食管受累，外观与该综合征的黏膜定位颇为相似。作者讨论了黑棘皮病食管定位与其他类型食管棘皮病或乳头状瘤相区别的特征。其中一例，这种类型的棘皮病发病七年后未出现任何可检测到的恶性变化，另一例患者在手术切除相关胃部肿瘤但未切除皮肤病变后，皮肤病变有所改善。
