Booth James R, Burman Douglas D, Meyer Joel R, Gitelman Darren R, Parrish Todd B, Mesulam M Marsel
Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA.
Neuroimage. 2002 May;16(1):7-22. doi: 10.1006/nimg.2002.1081.
Functional magnetic resonance imaging (fMRI) was used to examine lexical processing in normal adults (20-35 years). Two tasks required only intramodal processing (spelling judgments with visual input and rhyming judgments with auditory input) and two tasks required cross-modal processing between phonologic and orthographic representations (spelling judgments with auditory input and rhyming judgments with visual input). Each task led to greater activation in the unimodal association area concordant with the modality of input, namely fusiform gyrus (BA 19, 37) for written words and superior temporal gyrus (BA 22, 42) for spoken words. Cross-modal tasks generated greater activation in posterior heteromodal regions including the supramarginal and angular gyri (BA 40, 39). Cross-modal tasks generated additional activation in unimodal areas representing the target of conversion, superior temporal gyrus for visual rhyming and fusiform gyrus for auditory spelling. Our findings suggest that the fusiform gyrus processes orthographic word forms, the superior temporal gyrus processes phonologic word forms, and posterior heteromodal regions are involved in the conversion between orthography and phonology.
功能磁共振成像（fMRI）被用于研究正常成年人（20 - 35岁）的词汇加工过程。两项任务仅需要模态内加工（视觉输入的拼写判断和听觉输入的押韵判断），另外两项任务需要音韵和正字法表征之间的跨模态加工（听觉输入的拼写判断和视觉输入的押韵判断）。每项任务都会在与输入模态一致的单模态联合区域引发更强的激活，即对于书面文字，梭状回（BA 19、37）被激活；对于口语单词，颞上回（BA 22、42）被激活。跨模态任务在包括缘上回和角回（BA 40、39）在内的后部异模态区域产生更强的激活。跨模态任务在代表转换目标的单模态区域也产生了额外的激活，视觉押韵任务中颞上回被激活，听觉拼写任务中梭状回被激活。我们的研究结果表明，梭状回处理正字法单词形式，颞上回处理音韵学单词形式，而后部异模态区域参与正字法和音韵学之间的转换。
