Symptomatic therapy for underrecognized manifestations of multiple sclerosis.

The symptoms that affect individuals with MS are diverse and change over time. Addressing symptoms in a multidisciplinary fashion and helping patients address problems as they occur are the major elements of symptom management. Successful management involves treating not only the more readily recognized manifestations of MS but also the less apparent MS features, including fatigue, cognitive loss, mood disturbance, and pain. Management of these symptoms is reviewed.