Larousse Eric, Asehnoune Karim, Dartayet Bruno, Albaladejo Pierre, Dubousset Anne-Marie, Gauthier Frédéric, Benhamou Dan
Department of Anesthesiology and Critical Care Medicine, Centre hospitalo-universitaire du Kremlin Bicêtre, France.
Anesth Analg. 2002 May;94(5):1165-8, table of contents. doi: 10.1097/00000539-200205000-00020.
Pediatric caudal anesthesia is an effective method with an infrequent complication rate. However, little is known about its cardiovascular consequences. Transesophageal Doppler, a noninvasive method, provides the opportunity for a reappraisal of the hemodynamic effects of this technique. After parental informed consent, we studied 10 children aged 2 mo to 5 yr who were scheduled for lower abdominal surgery. General anesthesia was induced using sevoflurane and was followed by the insertion of a transesophageal Doppler probe. Caudal anesthesia was performed using 1 mL/kg of 0.25% bupivacaine with 1/200,000 epinephrine. Hemodynamic variables were collected before and after caudal anesthesia. No complications arose during insertion of the probe. The mean time between the two sets of measurements was 15 min. Heart rate, systolic, diastolic, and mean arterial blood pressures were not modified by caudal anesthesia. Descending aortic blood flow increased significantly from 1.14 to 1.92 L/min. (P = 0.0002). Aortic ejection volume increased from 8.5 to 14.5 mL (P = 0.0002). Aortic vascular resistances decreased from 6279 to 3901 dynes. s(-1) x m(-5) (P = 0.005). Caudal anesthesia did not affect heart rate and mean arterial blood pressure but induced a significant increase in descending aortic blood flow.
Although pediatric caudal anesthesia does not alter heart rate nor arterial blood pressure, significant changes occur in regional blood flow distribution. Descending aortic blood flow increases significantly after caudal anesthesia, whereas lower body vascular resistances decrease.
小儿骶管麻醉是一种有效方法,并发症发生率低。然而,其对心血管系统的影响却鲜为人知。经食管多普勒检查是一种非侵入性方法,为重新评估该技术的血流动力学效应提供了机会。在获得家长知情同意后,我们研究了10名年龄在2个月至5岁之间计划接受下腹部手术的儿童。使用七氟醚诱导全身麻醉,随后插入经食管多普勒探头。采用1 mL/kg的0.25%布比卡因加1/200,000肾上腺素进行骶管麻醉。在骶管麻醉前后收集血流动力学变量。探头插入过程中未出现并发症。两组测量之间的平均时间为15分钟。骶管麻醉未改变心率、收缩压、舒张压和平均动脉压。降主动脉血流量从1.14 L/min显著增加至1.92 L/min(P = 0.0002)。主动脉射血容积从8.5 mL增加至14.5 mL(P = 0.0002)。主动脉血管阻力从6279达因·秒-1·米-5降至3901达因·秒-1·米-5(P = 0.005)。骶管麻醉不影响心率和平均动脉压,但可使降主动脉血流量显著增加。
尽管小儿骶管麻醉不会改变心率和动脉血压,但区域血流分布会发生显著变化。骶管麻醉后降主动脉血流量显著增加,而下半身血管阻力降低。