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[内源性精神病中的血清肌酸磷酸激酶(CPK)]

[Serum creatinphosphokinase (CPK) in endogenic psychoses].

作者信息

Krüger E, Lohse H

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1975 Mar;27(3):140-6.

PMID:1197451
Abstract

Creatinphosphokinase (CPK) was determined in 141 patients with manic-depressive and schizophrenic psychoses. In general endogenic psychoses of the manic and depressive type as well as chronic schizophrenias show normal CPK values. In acute cases of paranoid-halluzinatory schizophrenias normal values are predominant. In catatonic schizophrenias, as a rule, clearly increased enzyme activities are found. Thise increased values suggest a postulated somatic disease as a cause of the psychosis. Thus, the determination of CPK provides a useful aid in the diagnosis and control of the course of catatonic schizophrenic.

摘要

对141例躁郁症和精神分裂症患者测定了肌酸磷酸激酶(CPK)。一般来说,躁狂和抑郁型的内源性精神病以及慢性精神分裂症患者的CPK值正常。在急性偏执-幻觉型精神分裂症病例中,正常值占主导。在紧张型精神分裂症中,通常会发现酶活性明显升高。这些升高的值表明存在一种假定的躯体疾病作为精神病的病因。因此,CPK的测定有助于紧张型精神分裂症的诊断和病程监测。

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