Krüger E, Lohse H
Psychiatr Neurol Med Psychol (Leipz). 1975 Mar;27(3):140-6.
Creatinphosphokinase (CPK) was determined in 141 patients with manic-depressive and schizophrenic psychoses. In general endogenic psychoses of the manic and depressive type as well as chronic schizophrenias show normal CPK values. In acute cases of paranoid-halluzinatory schizophrenias normal values are predominant. In catatonic schizophrenias, as a rule, clearly increased enzyme activities are found. Thise increased values suggest a postulated somatic disease as a cause of the psychosis. Thus, the determination of CPK provides a useful aid in the diagnosis and control of the course of catatonic schizophrenic.
对141例躁郁症和精神分裂症患者测定了肌酸磷酸激酶（CPK）。一般来说，躁狂和抑郁型的内源性精神病以及慢性精神分裂症患者的CPK值正常。在急性偏执-幻觉型精神分裂症病例中，正常值占主导。在紧张型精神分裂症中，通常会发现酶活性明显升高。这些升高的值表明存在一种假定的躯体疾病作为精神病的病因。因此，CPK的测定有助于紧张型精神分裂症的诊断和病程监测。
