Yacoub Ashraf, Martel M Jocelyne
Department of Obstetrics and Gynecology, University of Saskatchewan, Saskatoon, Canada. ashrafyacoub@hotmail..com
Obstet Gynecol. 2002 May;99(5 Pt 2):928-30. doi: 10.1016/s0029-7844(01)01745-8.
Primary dilated cardiomyopathy is rare in women of childbearing age. The expected increase in intravascular volume and cardiac output during pregnancy is poorly tolerated by patients with primary dilated cardiomyopathy and may result in cardiac failure.
A primigravid teenager with a history of primary dilated cardiomyopathy developed severe acute cardiac failure at 20 weeks' gestation. She required ventilation and was treated with inotropes and nitroglycerin. After counseling, she underwent termination of pregnancy using misoprostol. She recovered and was discharged 5 days after delivery.
Pregnancy in patients with primary dilated cardiomyopathy can be extremely hazardous, resulting in cardiac failure and even death. A multidisciplinary approach and consideration of termination of pregnancy may be required in management of such patients.
原发性扩张型心肌病在育龄女性中较为罕见。原发性扩张型心肌病患者对孕期血管内容量和心输出量的预期增加耐受性较差,可能导致心力衰竭。
一名有原发性扩张型心肌病病史的初产妇青少年在妊娠20周时发生严重急性心力衰竭。她需要通气,并接受了血管活性药物和硝酸甘油治疗。经过咨询,她使用米索前列醇终止了妊娠。她康复后,产后5天出院。
原发性扩张型心肌病患者怀孕可能极其危险,导致心力衰竭甚至死亡。对此类患者的管理可能需要多学科方法并考虑终止妊娠。