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男性和女性在卧床休息2 - 3周后的身体成分变化。

Body composition changes in men and women after 2-3 weeks of bed rest.

作者信息

Pace N, Kodama A M, Price D C, Grunbaum B W, Rahlmann D F, Newsom B D

机构信息

White Mountain Research Station, University of California, Berkeley, Calif., USA.

出版信息

Life Sci Space Res. 1976;14:269-74.

PMID:11977282
Abstract

Several parameters of body composition were measured in eight men before and after 14 days of continuous recumbency, and in eight women before and after 17 days of recumbency. The parameters measured included body weight, body water, body potassium, plasma volume, and plasma protein concentrations. From these, values were derived for body fat content, lean body mass, body cell mass, and circulating plasma proteins. In general, the men and women responded similarly to continuous recumbency. Characteristically, there was significant reduction of plasma volume and body potassium in both groups. The women showed a significant reduction in circulating plasma protein, entirely in the albumin fraction; a similar change was observed in the men. The women, but not the men, showed a significant increase in circulating fibrinogen. Both men and women lost body cell mass, while body fat content remained the same or tended to increase slightly. It is expected that similar changes would occur in weightlessness. It is further concluded that women should tolerate the weightlessness of space flight physiologically as well as men.

摘要

对8名男性在连续卧床14天前后,以及8名女性在连续卧床17天前后的多项身体成分参数进行了测量。测量的参数包括体重、身体水分、身体钾含量、血浆容量和血浆蛋白浓度。由此得出身体脂肪含量、瘦体重、身体细胞质量和循环血浆蛋白的值。总体而言,男性和女性对连续卧床的反应相似。其特点是,两组的血浆容量和身体钾含量均显著降低。女性的循环血浆蛋白显著减少,完全是白蛋白部分减少;男性也观察到类似变化。女性(而非男性)的循环纤维蛋白原显著增加。男性和女性的身体细胞质量均减少,而身体脂肪含量保持不变或略有增加趋势。预计在失重状态下会出现类似变化。进一步得出结论,女性在生理上应与男性一样耐受太空飞行的失重状态。

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