Röcker L, Kirsch K A, Stoboy H
Isr J Med Sci. 1978 Feb;14(2):212-7.
Healthy, sedentary women and men, aged 20 to 30 years, were exposed to the same degree of intermittent heat stress in a sauna bath. Blood samples were taken immediately before and at various intervals after heat exposure. The concentrations and intravascular masses of IgG, IgA, IgM, alpha1-antitrypsin, transferrin and alpha2-macroglobulin were determined by the radial immunodiffusion technique and by the measurement of plasma volume. Losses in body weight and plasma volume were lower in women than in men. The globulin concentrations increased significantly in both sexes after heat exposure. The sum of the masses of individual globulins increased only in women, a change interpreted as globulin shifts from the interstitial into the vascular space. Whereas it is unlikely that sex-dependent differences in these shifts are due to changes in vascular permeability, it seems that the protein composition of the lymphatic fluid entering the vascular space plays an important role in these shifts.
年龄在20至30岁之间、健康且久坐不动的女性和男性，在桑拿浴中接受相同程度的间歇性热应激。在热暴露前及热暴露后的不同时间间隔采集血样。采用放射免疫扩散技术并通过测量血浆容量来测定IgG、IgA、IgM、α1-抗胰蛋白酶、转铁蛋白和α2-巨球蛋白的浓度及血管内质量。女性的体重和血浆容量损失低于男性。热暴露后，两性的球蛋白浓度均显著升高。仅女性个体球蛋白的质量总和增加，这种变化被解释为球蛋白从间质向血管空间的转移。虽然这些转移中性别依赖性差异不太可能是由于血管通透性的变化，但进入血管空间的淋巴液的蛋白质组成似乎在这些转移中起重要作用。
