Zhang Liqiang, Luan Xinyong, Pan Xinliang, Xie Guang, Xu Fenglei, Liu Dali, Lei Dapeng
Department of Otorhinolaryngology, Qilu Hospital, Shandong University, Jinan 250012, China.
Zhonghua Zhong Liu Za Zhi. 2002 Jan;24(1):59-61.
To explore the surgical methods and evaluate the long-term result of laryngectomy in patients with supraglottic laryngeal cancer.
182 patients with supraglottic laryngeal carcinoma underwent operation from 1979 to 1999, with stage I 11, stage II 45, stage III 49 and stage IV 77 lesions. The choice of surgical procedure was decided with the disease condition of the larynx. The surgical procedures proposed by TD Wang were adhered to as: minor partial laryngectomy 36, major partial laryngectomy 85, subtotal partial laryngectomy with laryngoplasty 22 and total laryngectomy 39.
The ultimate rate of larynx preservation was 78.6% (143/182) with 69.8% (88/126) in stage III and IV diseases. The decannulation rate was 81.8% in cases with preservation of laryngeal function. The overall 3- and 5-year survival rates were 82.9% and 67.3%, with 76.88% and 57.4% in the advanced (stage III and IV) cases who survived with preserved laryngeal function. They were 82.5% and 67.0% in similar advanced cases who were treated by total laryngectomy. The difference in the survival rates between these two groups was not statistically significant.
It is suggested that preservation of the laryngeal function be possible for advanced supraglottic laryngeal carcinoma without compromising the remote survival rate. To improve the rate of larynx preservation, one should follow the surgical methods suggested.
探讨声门上型喉癌患者喉切除术的手术方法并评估其远期疗效。
1979年至1999年,182例声门上型喉癌患者接受了手术,其中Ⅰ期病变11例,Ⅱ期病变45例,Ⅲ期病变49例,Ⅳ期病变77例。根据喉部疾病情况决定手术方式的选择。遵循王德炳提出的手术方式为:次全喉部分切除术36例,全喉部分切除术85例,喉成形术的次全喉部分切除术22例,全喉切除术39例。
喉保留的最终率为78.6%(143/182),Ⅲ期和Ⅳ期疾病患者中为69.8%(88/126)。保留喉功能的患者拔管率为81.8%。总体3年和5年生存率分别为82.9%和67.3%,保留喉功能存活的晚期(Ⅲ期和Ⅳ期)病例中分别为76.88%和57.4%。全喉切除术治疗的类似晚期病例中分别为82.5%和67.0%。两组生存率差异无统计学意义。
提示对于晚期声门上型喉癌,在不影响远期生存率的情况下保留喉功能是可行的。为提高喉保留率,应遵循所建议的手术方法。