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老年晚期喉癌患者的手术治疗及喉功能保留

[Surgical management and preservation of laryngeal function for senile patients with advanced laryngeal carcinoma].

作者信息

Zhang Dao-gong, Zhang Han-bing, Luan Xin-yong, Pan Xin-liang, Xie Guang

机构信息

Department of Otolaryngology, Qilu Hospital, Shangdong University, Jinan 250012, China.

出版信息

Zhonghua Zhong Liu Za Zhi. 2007 May;29(5):379-81.

Abstract

OBJECTIVE

To explore the methods of surgical treatment and preservation of laryngeal function in senile patients with advanced laryngeal carcinoma.

METHODS

A retrospective data review of 87 advanced laryngeal carcinoma patients aged over 65 years was carried out. Of these 87 patients treated by different modes of surgery, 48 had supraglottic cancer, 35 glottic cancer and 4 subglottic cancer. The surgery modes consisted of major partial laryngectomy in 36 patients, subtotal partial laryngectomy with laryngoplasty in 21 and total laryngectomy in 30. All patients received postoperative radiotherapy to a dose of 50-60 Gy. Kaplan-Meier method was used to analyze the survival.

RESULTS

The overall 3- and 5-year survival rate was 73.2% and 67.4%, respectively. The ultimate rate of larynx preservation was 65.5%. Of 57 patients with partial laryngectomy, 46 were decannulated with a decannulation rate of 80.7%. Yet, in all patients, the nasal feeding tube was removed and food intake per os was resumed. All patients who underwent partial laryngectomy regained their phonation function.

CONCLUSION

It is safe and effective to treat and preserve laryngeal function surgically in the senile patients with advanced laryngeal carcinoma. The key points to achieve this are selection of proper patient, renovation of surgical procedure and improvement of surgical skill.

摘要

目的

探讨老年晚期喉癌患者的手术治疗方法及喉功能保留方法。

方法

对87例年龄65岁以上的晚期喉癌患者进行回顾性资料分析。这87例患者采用不同手术方式治疗,其中声门上癌48例,声门癌35例,声门下癌4例。手术方式包括36例行喉大部分切除术,21例行喉次全切除术加喉成形术,30例行全喉切除术。所有患者术后均接受50 - 60 Gy的放疗。采用Kaplan - Meier法分析生存率。

结果

3年和5年总生存率分别为73.2%和67.4%。喉保留最终率为65.5%。57例行部分喉切除术的患者中,46例拔管,拔管率为80.7%。而且,所有患者均拔除鼻饲管并恢复经口进食。所有接受部分喉切除术的患者均恢复了发声功能。

结论

手术治疗并保留老年晚期喉癌患者的喉功能是安全有效的。实现这一目标的关键在于选择合适的患者、改进手术方式和提高手术技巧。

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