Charalabopoulos Konstantin, Charalabopoulos Alexander, Binolis Jayne, Papalimneou Vicky, Ioachim Elli
Dept. of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, 13 Solomou str., 452 21 Ioannina, Greece.
In Vivo. 2002 Jan-Feb;16(1):73-6.
A 64 year-old Caucasian female of Greek origin was admitted to hospital with painful cervical and axillary lymphodenitis accompanied by fever and night sweats for 10 days. The patient had undergone a pacemaker implantation six weeks before disease onset because of heart conduction abnormalities. A diagnosis of Kikuchi-Fujimoto disease was established after lymph node biopsy. The etiology of the disease is unknown but viral, bacterial, protozoal; and neoplastic as well as physicochemical agents may stimulate a particular immune response. Hereby, we hypothesize that the implant pacemaker can act as a physicochemical agent triggering Kikuchi-Fujimoto disease. We present this case and we discuss various disease aspects. A brief review of the literature is also given.
一名64岁的希腊裔白种女性因颈部和腋窝疼痛性淋巴结炎入院，伴有发热和盗汗10天。该患者在疾病发作前六周因心脏传导异常接受了起搏器植入术。淋巴结活检后确诊为菊池-藤本病。该病病因不明，但病毒、细菌、原生动物、肿瘤以及物理化学因素可能刺激特定的免疫反应。因此，我们推测植入的起搏器可作为触发菊池-藤本病的物理化学因素。我们展示此病例并讨论疾病的各个方面，还对相关文献进行了简要综述。
