Loh John Ming Ren, Shafi Humaira
Department of General Medicine, Changi General Hospital, Singapore, Singapore.
BMJ Case Rep. 2014 Nov 24;2014:bcr2014205832. doi: 10.1136/bcr-2014-205832.
We present a case report of a 41-year-old woman of Malay ethnicity who presented with an 11-day history of fever and left-sided lymphadenopathy after consuming 'Miracle Mineral Solution' (sodium chlorite solution) for the first time. A diagnosis of Kikuchi-Fujimoto disease was established via lymph node biopsy after other differentials were excluded. The aetiology of Kikuchi-Fujimoto disease remains controversial, but viral, autoimmune and physicochemical causes have been suggested as possibilities. In this case, we hypothesise that oxidative injury from sodium chlorite initiated an inflammatory response, which triggered the onset of Kikuchi-Fujimoto disease.
我们报告一例41岁马来族女性病例,该患者在首次饮用“奇迹矿物溶液”(亚氯酸钠溶液)后出现了11天的发热和左侧淋巴结病病史。在排除其他鉴别诊断后,通过淋巴结活检确诊为菊池-藤本病。菊池-藤本病的病因仍存在争议,但病毒、自身免疫和物理化学原因被认为是可能的病因。在本病例中,我们推测亚氯酸钠引起的氧化损伤引发了炎症反应,从而触发了菊池-藤本病的发作。