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使用阿昔单抗和肝素成功治疗右心房血栓。

Right atrial thrombus treated successfully with abciximab and heparin.

作者信息

Borges A C, Reibis R K, Claus M, Baumann G

机构信息

Department of Cardiology, Angiology and Pneumology, Humboldt-University Hospital (Charité), Berlin, Germany.

出版信息

J Thromb Thrombolysis. 2001 Dec;12(3):283-7. doi: 10.1023/a:1015235326994.

DOI:10.1023/a:1015235326994
PMID:11981111
Abstract

We report here a case of right atrial thrombus diagnosed by echocardiography in a 25-year-old female patient with Hodgkin's disease receiving chemotherapy and heparin. After 24 hours therapy with the glycoprotein IIb/IIIa receptor antagonist (abciximab) with concomitant heparin the complete dissolution of the thrombus could be demonstrated by transesophageal echocardiography. To our knowledge this case represents the first use of abciximab in right atrial thrombosis.

摘要

我们在此报告一例25岁患霍奇金病且正在接受化疗和肝素治疗的女性患者，经超声心动图诊断为右心房血栓形成。在用糖蛋白IIb/IIIa受体拮抗剂（阿昔单抗）并同时使用肝素治疗24小时后，经食管超声心动图显示血栓已完全溶解。据我们所知，此病例是阿昔单抗首次用于右心房血栓形成的治疗。

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本文引用的文献

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Abciximab readministration: results of the ReoPro Readministration Registry.阿昔单抗再次给药：ReoPro再次给药登记研究结果
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Trousseau's syndrome treated with long-term subcutaneous lepirudin (case report and review of the literature).长期皮下注射比伐芦定治疗特鲁索综合征（病例报告及文献综述）
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Potential future clinical applications for the GPIIb/IIIa antagonist, abciximab in thrombosis, vascular and oncological indications.血小板糖蛋白IIb/IIIa拮抗剂阿昔单抗在血栓形成、血管和肿瘤适应症方面未来潜在的临床应用。
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Acute thromboscintigraphy with (99m)Tc-apcitide: results of the phase 3 multicenter clinical trial comparing 99mTc-apcitide scintigraphy with contrast venography for imaging acute DVT. Multicenter Trial Investigators.锝（99m）Tc -阿昔肽的急性血栓闪烁扫描：一项3期多中心临床试验的结果，该试验比较了99mTc -阿昔肽闪烁扫描与静脉造影对急性深静脉血栓形成的成像效果。多中心试验研究者
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