Wilson P D, Salvati E A, Blumenfeld E L
Surg Clin North Am. 1975 Dec;55(6):1431-7. doi: 10.1016/s0039-6109(16)40803-0.
In summary, deep wound infection carries a special and disastrous significance for the patient with a total joint prosthesis. Such patients seem to be at greater than usual risk of infection, and special precautionary measures to prevent it are not only justified but imperative. These include careful preoperative preparation; special attention to rigid and exacting operative techniques for control of potential exogenous contaminants; sensible preoperative, intraoperative, and postoperative antibiotic prophylaxis for control of potential endogenous cantaminants; and continued supervision of the patient throughout the postoperative years so as to prevent potential metastatic infection from other primary sources. Pre-existing and active infections of the hip constitute contraindications to total prosthetic arthroplasty, but these rules may be suspended in certain special situations provided that the patient is willing to cooperate with the arduous and prolonged program of treatment, and fully understands the special risks involved.
总之，深部伤口感染对于全关节置换患者具有特殊且灾难性的意义。这类患者似乎比一般人有更高的感染风险，采取特殊的预防措施不仅合理而且势在必行。这些措施包括术前仔细准备；特别注重严格且精确的手术技术以控制潜在的外源性污染物；合理进行术前、术中和术后抗生素预防以控制潜在的内源性污染物；以及在术后数年持续对患者进行监测，以防止其他原发部位的潜在转移性感染。髋部先前存在的活动性感染是全关节置换术的禁忌证，但在某些特殊情况下，只要患者愿意配合艰巨且长期的治疗方案，并充分了解其中涉及的特殊风险，这些规则可以暂停执行。
