乔克托族印第安人中载脂蛋白E4和tau等位基因频率
Apolipoprotein E4 and tau allele frequencies among Choctaw Indians.
作者信息
Henderson J Neil, Crook Richard, Crook Julia, Hardy John, Onstead Luisa, Carson-Henderson Linda, Mayer Pat, Parker Bea, Petersen Ronald, Williams Birdie
机构信息
Department of Health Promotion Sciences, University of Oklahoma, Oklahoma City 73190, USA.
出版信息
Neurosci Lett. 2002 May 10;324(1):77-9. doi: 10.1016/s0304-3940(02)00150-7.
Apolipoprotein genotyping and tau haplotyping were carried out on a series of cases with dementia and controls from the Choctaw Nation of Oklahoma. Both the Apolipoprotein E4 allele frequency and the tau H2 haplotype frequency were low in the Choctaw compared with Caucasians and there was the possibility that the association between dementia and the E4 allele was weaker than in Caucasians.
对来自俄克拉荷马州乔克托族的一系列痴呆症病例和对照进行了载脂蛋白基因分型和tau单倍型分型。与高加索人相比，乔克托族的载脂蛋白E4等位基因频率和tau H2单倍型频率均较低，并且痴呆症与E4等位基因之间的关联可能比高加索人弱。
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