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刚果锥虫在感染多乳鼠(非洲巨颊囊鼠)中的分布:光镜和电镜研究

Distribution of Trypanosoma congolense in infected multimammate rats (Mastomys coucha): light and electron microscopical studies.

作者信息

Ojok L, Kaeufer-Weiss I, Weiss E

机构信息

Department of Veterinary Pathology, Faculty of Veterinary Medicine, Makerere University, P.O. Box 7062, Kampala, Uganda.

出版信息

Vet Parasitol. 2002 May 10;105(4):327-36. doi: 10.1016/s0304-4017(02)00017-1.

DOI:10.1016/s0304-4017(02)00017-1
PMID:11983307
Abstract

In an attempt to determine whether Trypanosoma congolense occurs both within and outside the blood vessels in an infected animal host, multimammate rats (Mastomys coucha) were infected with T. congolense and samples from spleen, lymph nodes, bone marrow, liver, kidney, lungs, brain, heart, intestines, ovaries and testes were collected. The tissue samples were fixed and processed for light and electron microscopical examination. In all the tissues examined, trypanosomes were found only within the lumen of large and small blood vessels, capillaries and sinuses. It is concluded that following entry into the blood circulation after intra-peritoneal infection of M. coucha, T. congolense remains restricted to the bloodstream.

摘要

为了确定刚果锥虫在受感染动物宿主体内的血管内外是否均有存在,将多乳鼠(非洲巨鼠)感染刚果锥虫,并采集脾脏、淋巴结、骨髓、肝脏、肾脏、肺、脑、心脏、肠道、卵巢和睾丸的样本。组织样本经固定后进行光镜和电镜检查。在所有检查的组织中,仅在大、小血管、毛细血管和血窦腔内发现锥虫。得出的结论是,在多乳鼠经腹腔感染后进入血液循环后,刚果锥虫仍局限于血流中。

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