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Host background immunity and human immunodeficiency virus protective vaccines, a major consideration for vaccine efficacy in Africa and in developing countries.

作者信息

Borkow Gadi, Bentwich Zvi

机构信息

R. Ben-Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot, Israel.

出版信息

Clin Diagn Lab Immunol. 2002 May;9(3):505-7. doi: 10.1128/cdli.9.3.505-507.2002.

DOI:10.1128/cdli.9.3.505-507.2002
PMID:11986252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC119996/
Abstract
摘要

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本文引用的文献

1
The global burden of intestinal nematode infections--fifty years on.五十年后的肠道线虫感染全球负担
Parasitol Today. 1997 Nov;13(11):438-43. doi: 10.1016/s0169-4758(97)01144-7.
2
Helminths, human immunodeficiency virus and tuberculosis.蠕虫、人类免疫缺陷病毒与结核病
Scand J Infect Dis. 2001;33(8):568-71. doi: 10.1080/00365540110026656.
3
The global impact of HIV/AIDS.艾滋病毒/艾滋病的全球影响。
Nature. 2001 Apr 19;410(6831):968-73. doi: 10.1038/35073639.
4
Induction of antigen-specific Th1-biased immune responses by plasmid DNA in schistosoma-infected mice with a preexistent dominant Th2 immune profile.在具有预先存在的主导性Th2免疫特征的血吸虫感染小鼠中，质粒DNA诱导抗原特异性Th1偏向性免疫反应。
Biochem Biophys Res Commun. 2001 Apr 20;282(5):1169-76. doi: 10.1006/bbrc.2001.4698.
5
Effect of deworming on human T cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacille Calmette-Guérin (BCG) vaccination.驱虫对卡介苗（BCG）接种前后受蠕虫感染个体中人类T细胞对分枝杆菌抗原反应的影响。
Clin Exp Immunol. 2001 Feb;123(2):219-25. doi: 10.1046/j.1365-2249.2001.01446.x.
6
Chronic immune activation associated with intestinal helminth infections results in impaired signal transduction and anergy.与肠道蠕虫感染相关的慢性免疫激活会导致信号转导受损和无反应性。
J Clin Invest. 2000 Oct;106(8):1053-60. doi: 10.1172/JCI10182.
7
Good worms or bad worms: do worm infections affect the epidemiological patterns of other diseases?有益蠕虫还是有害蠕虫：蠕虫感染会影响其他疾病的流行模式吗？
Parasitol Today. 2000 Jul;16(7):312. doi: 10.1016/s0169-4758(00)01693-8.
8
Reduction in interleukin-2-producing cells but not Th1 to Th2 shift in moderate and advanced stages of human immunodeficiency virus type-1-infection: direct analysis of intracellular cytokine concentrations in CD4+ CD8- T cells.人类免疫缺陷病毒1型感染中晚期白细胞介素-2产生细胞减少，但Th1向Th2无偏移：对CD4+CD8-T细胞内细胞因子浓度的直接分析
Scand J Immunol. 1999 Nov;50(5):550-4. doi: 10.1046/j.1365-3083.1999.00627.x.
9
Infection by different HIV-1 subtypes (B and C) results in a similar immune activation profile despite distinct immune backgrounds.尽管免疫背景不同，但感染不同的HIV-1亚型（B型和C型）会导致相似的免疫激活情况。
J Acquir Immune Defic Syndr. 1999 Jun 1;21(2):157-63.
10
Decreased CD4 and increased CD8 counts with T cell activation is associated with chronic helminth infection.随着T细胞活化，CD4计数降低和CD8计数增加与慢性蠕虫感染相关。
Clin Exp Immunol. 1998 Dec;114(3):414-21. doi: 10.1046/j.1365-2249.1998.00736.x.