Oringer Richard J
J Periodontol. 2002 Apr;73(4):460-70. doi: 10.1902/jop.2002.73.4.460.
This paper was prepared by the Research, Science, and Therapy Committee of the American Academy of Periodontology to provide the dental profession an overview of current and potential methods to modulate the host response in the treatment of periodontal diseases. Specifically, it discusses components of periodontal disease pathogenesis (i.e., immune and inflammatory responses, excessive production of matrix metalloproteinases and arachidonic acid metabolites, and regulation of bone metabolism) and their modulation.
本文由美国牙周病学会研究、科学与治疗委员会撰写，旨在为牙科专业人士概述在牙周疾病治疗中调节宿主反应的现有及潜在方法。具体而言，本文讨论了牙周病发病机制的组成部分（即免疫和炎症反应、基质金属蛋白酶和花生四烯酸代谢产物的过度产生以及骨代谢的调节）及其调节。
