Lachnit-Fixson U
MMW Munch Med Wochenschr. 1979 Oct 26;121(43):1421-6.
The controlled clinical trial is reported of a new three-stage oral contraceptive which has meanwhile been introduced on to the market under the trade name Triquilar. Triquilar has a reliable contraceptive action: no pregnancy occurred in 8068 treatment cycles. In spite of the very low doses of estrogen and gestagen--Triquilar contains the lowest total quantity of steroids of all available preparations--the multistage structure guarantees an outstanding cycle control and a particularly good general tolerance. The reasons are discussed which today support the use of an oral contraceptive with the lowest possible amounts of the two hormone components.
报道了一项关于一种新型三阶段口服避孕药的对照临床试验，该避孕药已以商品名Triquilar投放市场。Triquilar具有可靠的避孕作用：在8068个治疗周期中未发生妊娠。尽管雌激素和孕激素的剂量非常低——Triquilar所含类固醇总量在所有现有制剂中是最低的——但其多阶段结构保证了出色的周期控制和特别好的总体耐受性。文中讨论了目前支持使用两种激素成分含量尽可能低的口服避孕药的原因。
