Taub Edward, Uswatte Gitrenda, Elbert Thomas
Birmingham Veterans Affairs Medical Center and Department of Psychology, University of Alabama at Birmingham, CPM 712, 1530 3rd Avenue South, Birmingham, Alabama 35294-0018, USA.
Nat Rev Neurosci. 2002 Mar;3(3):228-36. doi: 10.1038/nrn754.
Recent discoveries about how the central nervous system responds to injury and how patients reacquire lost behaviours by training have yielded promising new therapies for neurorehabilitation. Until recently, this field had been largely static, but the current melding of basic behavioural science with neuroscience promises entirely new approaches to improving behavioural, perceptual and cognitive capabilities after neurological damage. Studies of phenomena such as cortical reorganization after a lesion, central nervous system repair, and the substantial enhancement of extremity use and linguistic function by behavioural therapy, support this emerging view. The ongoing changes in rehabilitation strategies might well amount to an impending paradigm shift in this field.
最近关于中枢神经系统如何对损伤做出反应以及患者如何通过训练重新获得丧失行为的发现,为神经康复带来了前景广阔的新疗法。直到最近,该领域在很大程度上一直处于停滞状态,但当前基础行为科学与神经科学的融合有望为改善神经损伤后的行为、感知和认知能力带来全新方法。对诸如损伤后皮质重组、中枢神经系统修复以及行为疗法对肢体使用和语言功能的显著增强等现象的研究,支持了这一新兴观点。康复策略正在发生的变化很可能意味着该领域即将出现范式转变。