Vinogradov Evgeny V, Lindner Buko, Kocharova Nina A, Senchenkova Sof'ya N, Shashkov Aleksander S, Knirel Yuriy A, Holst Otto, Gremyakova Tat'yana A, Shaikhutdinova Rima Z, Anisimov Andrei P
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt 47,Moscow 119991, Russia.
Carbohydr Res. 2002 Apr 30;337(9):775-7. doi: 10.1016/s0008-6215(02)00074-5.
The rough-type lipopolysaccharide (LPS) of the plague pathogen, Yersinia pestis, was studied after mild-acid and strong-alkaline degradations by chemical analyses, NMR spectroscopy and electrospray-ionization mass spectrometry, and the following structure of the core region was determined:where L-alpha-D-Hep stands for L-glycero-alpha-D-manno-heptose, Sug1 for either 3-deoxy-alpha-D-manno-oct-2-ulosonic acid (alpha-Kdo) or D-glycero-alpha-D-talo-oct-2-ulosonic acid (alpha-Ko), and Sug2 for either beta-D-galactose or D-glycero-alpha-D-manno-heptose. A minority of the LPS molecules lacks GlcNAc.
通过化学分析、核磁共振光谱和电喷雾电离质谱对鼠疫病原体耶尔森氏鼠疫杆菌的粗糙型脂多糖（LPS）进行了温和酸降解和强碱降解研究，确定了核心区域的以下结构：其中L-α-D-庚糖代表L-甘油-α-D-甘露庚糖，Sug1代表3-脱氧-α-D-甘露辛-2-酮糖酸（α-Kdo）或D-甘油-α-D-塔罗辛-2-酮糖酸（α-Ko），Sug2代表β-D-半乳糖或D-甘油-α-D-甘露庚糖。少数LPS分子缺乏N-乙酰葡糖胺。
