Ito Ryuta, Mori Susumu, Melhem Elias R
Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan.
Neuroimaging Clin N Am. 2002 Feb;12(1):1-19. doi: 10.1016/s1052-5149(03)00067-4.
Diffusion-tensor MR imaging is a promising tool to evaluate white-matter integrity by quantitative and graphic maps including neural fiber tractogram. Current challenges afoot are to obtain higher quality diffusion-weighted MR images (high SNR, isotropic voxel, and high spatial resolution), to create a robust mathematical framework to process the data, to construct a user-friendly computer-based algorithm, to reveal determinants of diffusion process, and to establish analytical methodology.
扩散张量磁共振成像（Diffusion-tensor MR imaging）是一种很有前景的工具，可通过包括神经纤维束成像在内的定量和图形化图谱来评估白质完整性。当前面临的挑战包括获取更高质量的扩散加权磁共振图像（高信噪比、各向同性体素和高空间分辨率），创建一个强大的数学框架来处理数据，构建一个用户友好的基于计算机的算法，揭示扩散过程的决定因素，以及建立分析方法。
