Mayer P J, Beeken W L
Am J Dig Dis. 1975 Nov;20(11):1003-9. doi: 10.1007/BF01071187.
To evaluate the role of urinary indican excretion and several common absorptive tests as predictors of bacterial colonization in the human jejunum, we analyzed the relationship between indican excretion and quantitative jejunal cultures, tryptophan absorption, enteric protein loss, fecal nitrogen excretion, D-xylose and lactose tolerance tests, and B12 and fat absorption in 40 subjects. Indican excretion correlated poorly with jejunal colony counts (r = 0.22). Neither tryptophan load or absorption, nor nitrogen excretion were related to indicanuria, but there was a modest correlation between enteric protein loss and urinary indican values (r = 0.54). Lactose tolerance tests and D-xylose, B12 and fat absorption showed no predictive value for identifying patients with high colony counts. Compared to quantitative small bowel culture, none of the tests studied provided suitable methods for screening for bacterial contamination of the human jejunum.
为评估尿中吲哚苷排泄及几种常见吸收试验作为人类空肠细菌定植预测指标的作用，我们分析了40名受试者中吲哚苷排泄与空肠定量培养、色氨酸吸收、肠道蛋白丢失、粪便氮排泄、D-木糖和乳糖耐量试验以及维生素B12和脂肪吸收之间的关系。吲哚苷排泄与空肠菌落计数的相关性较差（r = 0.22）。色氨酸负荷或吸收以及氮排泄均与吲哚尿无关，但肠道蛋白丢失与尿中吲哚苷值之间存在适度相关性（r = 0.54）。乳糖耐量试验以及D-木糖、维生素B12和脂肪吸收对识别高菌落计数患者无预测价值。与定量小肠培养相比，所研究的试验均未提供适合筛查人类空肠细菌污染的方法。
