Kirkland J L, Vargas E, Lye M
Postgrad Med J. 1983 Nov;59(697):717-9. doi: 10.1136/pgmj.59.697.717.
It has been suggested that up to a half of elderly hospitalized patients excrete an abnormally high concentration of indican compared with young individuals. Thus, the commonly used colorimetric qualitative test for urinary indican excess may be invalid in the aged. However, of 21 young control subjects, 18 healthy elderly subjects, and 23 disabled, elderly, long-stay patients, no individual had levels of indican detectable by the standard colorimetric qualitative test. The use of a quantitative assay demonstrated that urinary indican concentration is similar in young and elderly individuals. A diurnal variation in urinary indican concentration was discovered which may affect the interpretation of the qualitative test.
有人提出，与年轻人相比，多达一半的老年住院患者排泄的吲哚氰浓度异常高。因此，常用的尿吲哚氰过量比色定性试验在老年人中可能无效。然而，在21名年轻对照受试者、18名健康老年受试者和23名残疾、老年、长期住院患者中，没有一个人的吲哚氰水平可通过标准比色定性试验检测到。定量分析表明，年轻人和老年人的尿吲哚氰浓度相似。发现尿吲哚氰浓度存在昼夜变化，这可能会影响定性试验的结果解读。
