McMahon R T, Tso M O, McLean I W
Am J Ophthalmol. 1975 Dec;80(6):1058-65. doi: 10.1016/0002-9394(75)90336-0.
We studied the distribution pattern of sodium fluorescein in human eyes microscopically. The ciliary body showed early and diffuse leakage, with staining of the basement membrane of the nonpigmented ciliary epithelium, indicating movement of fluorescein from the ciliary body into the aqueous humor. After five minutes the iris stroma stained with fluorescein, probably from the aqueous humor. The retinal vessels and retinal pigment epithelium were impermeable to fluorescein. Corresponding to the background fluorescence seen in fluorescein angiography, fluorescence was present in Bruch's membrane and in the stroma of the inner one third of the choroid. Drusen stained most intensely in areas of greatest PAS positively. Early fluorescence of the optic disk was the result of intravascular perfusion of the dye. Minimal diffusion of fluorescein from the fenestrated choroidal vessels across the border tissue of Elschnig into the peripheral optic nerve bundles was observed. Late fluorescene of the optic disk was due mainly to fluorescein staining of the lamina scleralis and glial columns.
我们通过显微镜研究了荧光素钠在人眼中的分布模式。睫状体显示出早期和弥漫性渗漏，无色素睫状上皮的基底膜有染色，表明荧光素从睫状体进入房水。五分钟后，虹膜基质被荧光素染色，可能来自房水。视网膜血管和视网膜色素上皮对荧光素是不透性的。与荧光素血管造影中看到的背景荧光相对应，布鲁赫膜和脉络膜内三分之一的基质中存在荧光。玻璃膜疣在PAS阳性最强的区域染色最深。视盘的早期荧光是染料血管内灌注的结果。观察到荧光素从有窗孔的脉络膜血管穿过埃尔施尼格边界组织向周边视神经束的最小扩散。视盘的晚期荧光主要是由于巩膜板和神经胶质柱的荧光素染色。
