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雌激素与雄激素联合制剂的随机临床试验:对性功能的影响。

Randomized clinical trials of combined estrogen-androgen preparations: effects on sexual functioning.

作者信息

Sherwin Barbara B

机构信息

Departments of Psychology and Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada.

出版信息

Fertil Steril. 2002 Apr;77 Suppl 4:S49-54. doi: 10.1016/s0015-0282(02)03002-9.

DOI:10.1016/s0015-0282(02)03002-9
PMID:12007902
Abstract

OBJECTIVE

To review the randomized controlled trials of the efficacy of combined estrogen-androgen (E-A) preparations on sexual functioning in postmenopausal women.

PATIENT(S): Naturally and surgically menopausal women.

MAIN OUTCOME MEASURE(S): Changes in aspects of sexual functioning.

RESULT(S): In general, a high degree of agreement exists among the findings of these well-controlled trials that combined E-A preparations enhance psychological well-being as well as sexual desire and interest and, sometimes, increases the frequency of sexual intercourse and orgasm compared with estrogen-alone treatment in both naturally and surgically postmenopausal women.

CONCLUSION(S): In selected cases, combined E-A therapy can enhance the quality of life for both naturally and surgically postmenopausal women.

摘要

目的

回顾联合雌激素 - 雄激素(E - A)制剂对绝经后女性性功能疗效的随机对照试验。

患者

自然绝经和手术绝经的女性。

主要观察指标

性功能各方面的变化。

结果

总体而言,这些严格对照试验的结果高度一致,即与单独使用雌激素治疗相比,联合E - A制剂可增强自然绝经和手术绝经女性的心理健康以及性欲和性兴趣,有时还可增加性交频率和性高潮频率。

结论

在特定情况下,联合E - A疗法可提高自然绝经和手术绝经女性的生活质量。

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