Gokhberg S L, Rasulev N I
Arkh Patol. 1975;37(4):55-60.
Electron-microscopy studies of biopsy specimens of the large intestine mucosa in 36 patients with non-specific ulcerated colitis were carried out. A difference in the structure of the lateral plasmatic membranes of prismatic cells and intercellular space of the large intestine mucosa in patients at periods of remission and exacerbation was revealed. Characteristics of the fine structure of the lateral plasmatic membranes of prismatic cells and the intercellular space in patients at the period of exacerbation of the disease reflected the compensatory processes directed at stabilization of the impaired water balance under conditions of diarrhea and dehydration by activating resorption processes in the large intestine.
对36例非特异性溃疡性结肠炎患者的大肠黏膜活检标本进行了电子显微镜研究。结果显示,在缓解期和加重期,患者大肠黏膜柱状细胞侧质膜结构及细胞间隙存在差异。疾病加重期患者柱状细胞侧质膜及细胞间隙的超微结构特征反映了在腹泻和脱水情况下,通过激活大肠重吸收过程来稳定受损水平衡的代偿过程。