辅酶Q对大鼠肝脏线粒体中胆碱氧化的必要性。
Essentiality of ubiquinone for choline oxidation in rat liver mitochondria.
作者信息
Barrett M C, Dawson A P
出版信息
Biochem J. 1975 Jun;148(3):595-7. doi: 10.1042/bj1480595.
Abstract
Rat liver mitochondria treated extensively with n-pentane are incapable of oxidizing choline. Choline oxidation is more sensitive than is succinate oxidation to serial n-pentane extraction of mitochondria. The ability to oxidize choline is restored by the addition of ubiquinone-2 or ubiquinone-10 to the oxidase assay medium.
摘要
用正戊烷大量处理过的大鼠肝脏线粒体无法氧化胆碱。胆碱氧化比琥珀酸氧化对线粒体的系列正戊烷提取更为敏感。通过向氧化酶分析培养基中添加泛醌-2或泛醌-10，氧化胆碱的能力得以恢复。
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