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分节丝状菌与上皮内单核细胞相互作用。

Segmented filamentous bacteria interact with intraepithelial mononuclear cells.

作者信息

Meyerholz David K, Stabel Thomas J, Cheville Norman F

机构信息

Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa 50010, USA.

出版信息

Infect Immun. 2002 Jun;70(6):3277-80. doi: 10.1128/IAI.70.6.3277-3280.2002.

DOI:10.1128/IAI.70.6.3277-3280.2002
PMID:12011024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC128008/
Abstract

Segmented filamentous bacteria (SFB) are found in multiple species and play an important role in the development of mucosal immunity. The mechanism by which the bacteria interact with the immune system has not been well defined. We provide morphologic evidence of direct interaction between SFB and intraepithelial mononuclear cells.

摘要

分节丝状菌（SFB）存在于多种物种中，在黏膜免疫的发育中发挥重要作用。细菌与免疫系统相互作用的机制尚未明确。我们提供了分节丝状菌与上皮内单核细胞直接相互作用的形态学证据。

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Segmented filamentous bacteria interact with intraepithelial mononuclear cells.分节丝状菌与上皮内单核细胞相互作用。
Infect Immun. 2002 Jun;70(6):3277-80. doi: 10.1128/IAI.70.6.3277-3280.2002.
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本文引用的文献

1
Segmented filamentous bacteria in the rodent small intestine: Their colonization of growing animals and possible role in host resistance toSalmonella.肠道中分段丝状细菌：它们在生长中的动物中的定植及其在宿主抵抗沙门氏菌中的可能作用。
Microb Ecol. 1982 Oct;8(2):181-90. doi: 10.1007/BF02010451.
2
Timing, localization, and persistence of colonization by segmented filamentous bacteria in the neonatal mouse gut depend on immune status of mothers and pups.新生小鼠肠道中分段丝状细菌的定殖时间、定位和持续性取决于母鼠和幼鼠的免疫状态。
Infect Immun. 2001 Jun;69(6):3611-7. doi: 10.1128/IAI.69.6.3611-3617.2001.
3
The role of dendritic cells, B cells, and M cells in gut-oriented immune responses.树突状细胞、B细胞和M细胞在肠道免疫反应中的作用。
J Immunol. 2001 Apr 15;166(8):4843-52. doi: 10.4049/jimmunol.166.8.4843.
4
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria.树突状细胞表达紧密连接蛋白，并穿透肠道上皮单层以采样细菌。
Nat Immunol. 2001 Apr;2(4):361-7. doi: 10.1038/86373.
5
Transmission electron microscopic demonstration of phagocytosis and intracellular processing of segmented filamentous bacteria by intestinal epithelial cells of the chick ileum.鸡回肠肠上皮细胞对分节丝状菌的吞噬作用及细胞内加工过程的透射电子显微镜观察
Infect Immun. 2000 Nov;68(11):6496-504. doi: 10.1128/IAI.68.11.6496-6504.2000.
6
Segmented filamentous bacteria prevent colonization of enteropathogenic Escherichia coli O103 in rabbits.分节丝状菌可防止肠道致病性大肠杆菌O103在兔体内定殖。
J Infect Dis. 2000 Mar;181(3):1027-33. doi: 10.1086/315348.
7
Differential roles of segmented filamentous bacteria and clostridia in development of the intestinal immune system.分节丝状菌和梭菌在肠道免疫系统发育中的不同作用。
Infect Immun. 1999 Jul;67(7):3504-11. doi: 10.1128/IAI.67.7.3504-3511.1999.
8
Interactions between gut-associated lymphoid tissue and colonization levels of indigenous, segmented, filamentous bacteria in the small intestine of mice.小鼠小肠中肠道相关淋巴组织与本土分节丝状菌定植水平之间的相互作用。
Can J Microbiol. 1998 Dec;44(12):1177-82. doi: 10.1139/cjm-44-12-1177.
9
Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gut mucosal immune system.分节丝状菌是小鼠肠道黏膜免疫系统生理正常状态的强效刺激物。
Infect Immun. 1999 Apr;67(4):1992-2000. doi: 10.1128/IAI.67.4.1992-2000.1999.
10
Kinetics of particle uptake in the domes of Peyer's patches.派尔集合淋巴结穹窿区颗粒摄取的动力学
Am J Physiol. 1998 Jul;275(1):G130-7. doi: 10.1152/ajpgi.1998.275.1.G130.