Watanabe M, Yoshida Y, Watanabe M, Shimada M, Kurimoto K
Br J Ind Med. 1975 Nov;32(4):316-20. doi: 10.1136/oem.32.4.316.
Distribution of radioactive carbon from [U-14C]glucose in the mouse poisoned by hydrofluoric acid has been studied by whole-body autoradiography. Under normal conditions, the highest autoradiographic density was found in the Harder's gland, palatine gland, sublingual gland, large intestinal mucosa, and many regions of the central nervous system 30 minutes after intraperitoneal injection of [U-14C]glucose. On the other hand, after hydrofluoric acid poisoning, it was found that (1) the radioactivity of brain was unchanged throughout all the poisoning; (2) the liver, renal cortex, lung, and blood showed an increase in radioactivity at 180 minutes of poisoning; (3) the abdominal cavity showed a tendency to residual radioactivity with the poisoning; (4) by contrast, Harder's gland, the palatine gland, sublingual gland, and large intestinal mucosa showed a decrease in radioactivity at 180 minutes of poisoning.
通过全身放射自显影术研究了[U-14C]葡萄糖中的放射性碳在氢氟酸中毒小鼠体内的分布情况。在正常情况下，腹腔注射[U-14C]葡萄糖30分钟后，在哈德氏腺、腭腺、舌下腺、大肠黏膜以及中枢神经系统的许多区域发现了最高的放射自显影密度。另一方面，在氢氟酸中毒后，发现：（1）在整个中毒过程中大脑的放射性没有变化；（2）在中毒180分钟时，肝脏、肾皮质、肺和血液的放射性增加；（3）腹腔随着中毒呈现出放射性残留的趋势；（4）相比之下，在中毒180分钟时，哈德氏腺、腭腺、舌下腺和大肠黏膜的放射性降低。
