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尽管存在诊断延迟,但采用创新的手术切除医疗管理方法成功治疗了肺毛霉菌病。

Innovative medical management with resection for successful treatment of pulmonary mucormycosis despite diagnostic delay.

作者信息

MacKenzie Karen M, Baumgarten Katherine L, Helm Boyd M, McFadden P Michael, Deduska Nicholas J, Loss George E, Eason James D

机构信息

Surgery Department, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.

出版信息

J La State Med Soc. 2002 Mar-Apr;154(2):82-5.

PMID:12014459
Abstract

We present a case of primary pulmonary mucormycosis infection in a renal transplant recipient diagnosed serendipitously by computed tomography scan. Treatment included discontinuation of immunosuppressive regimen, initiation of antifungal therapy with amphotericin B lipid complex, administration of granulocyte-macrophage colony stimulating factor, surgical excision of the involved lobe, and outpatient treatment with amphotericin B with dialysis. The patient ultimately required transplant nephrectomy as a result of immunosuppression discontinuation.

摘要

我们报告一例肾移植受者原发性肺毛霉菌病感染病例,该病例通过计算机断层扫描意外确诊。治疗措施包括停用免疫抑制方案、启动两性霉素B脂质体复合物抗真菌治疗、给予粒细胞巨噬细胞集落刺激因子、手术切除受累肺叶以及门诊使用两性霉素B联合透析治疗。由于停用免疫抑制治疗,患者最终需要进行移植肾切除术。

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