Gebel J, Sonntag H-G, Werner H-P, Vacata V, Exner M, Kistemann T
Committee for Disinfectants, German Society for Hygiene and Microbiology (DGHM), c/o Institute of Hygiene and Public Health, University of Bonn, Bonn, Germany.
J Hosp Infect. 2002 Apr;50(4):309-11. doi: 10.1053/jhin.2002.1201.
The Children's Clinic in Giessen, Germany recently reported several severe infections with Klebsiella oxytoca resulting in deaths of two neonates. The putative source of the infections was a contaminated infusion solution. The resistance to disinfectant of the K. oxytoca isolates was investigated in three independent laboratories and was indeed found to be significantly increased. Comparative tests with standard strains of K. oxytoca and other recommended bacterial surrogates showed the disinfection procedures used were fully effective. The higher resistance of the nosocomial isolates may have developed due to improper handling and storage of the cleaning utensils. This report describes the events and draws conclusions concerning the use of disinfectants, the treatment of cleaning utensils, the reliability of procedures for testing disinfectants, and suggests additional measures.
德国吉森市的儿童诊所最近报告了几起由产酸克雷伯菌引起的严重感染事件，导致两名新生儿死亡。感染的推定来源是一种受污染的输液溶液。在三个独立实验室对产酸克雷伯菌分离株的消毒剂抗性进行了调查，结果发现其抗性确实显著增加。与产酸克雷伯菌标准菌株和其他推荐的细菌替代物进行的对比试验表明，所使用的消毒程序完全有效。医院分离株较高的抗性可能是由于清洁用具处理和储存不当所致。本报告描述了这些事件，并就消毒剂的使用、清洁用具的处理、消毒剂测试程序的可靠性得出结论，并提出了额外措施。
