雄性生殖细胞的特化与分化。
Male germ cell specification and differentiation.
作者信息
Zhao Guang Quan, Garbers David L
机构信息
Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical School, Dallas, TX 75390, USA.
出版信息
Dev Cell. 2002 May;2(5):537-47. doi: 10.1016/s1534-5807(02)00173-9.
Abstract
Understanding the mechanisms by which the germline is induced and maintained should lead to a broader understanding of the means by which pluripotency is acquired and maintained. In this review, two major aspects of male germ cell development are discussed: underlying mechanisms for induction and maintenance of primordial germ cells and the basic signaling pathways that determine spermatogonial cell fate.
摘要
了解生殖系被诱导和维持的机制，应该能更广泛地理解多能性获得和维持的方式。在这篇综述中，讨论了雄性生殖细胞发育的两个主要方面：原始生殖细胞诱导和维持的潜在机制，以及决定精原细胞命运的基本信号通路。
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