Yi Y, Cao Z, Yang D, Cao Y, Wu Y, Zhao S
Jiangsu Province Institute of Materia Medica, China Pharmaceutical University, Nanjing 210009.
Yao Xue Xue Bao. 1998 Nov;33(11):873-5.
Smilax glabra is a well-known traditional Chinese medicine which has been used clinically to prevent leptospirosis, to treat syphilis, and acute bacterial dysentery, etc. Its extracts showed anti-tumor and anti-atherosclerosis activity. A new isoflavone, 7,6'-dihydroxy 3'-methoxy isoflavone (1), along with two known compounds taxifolin (2) and astilbin (3), have been isolated from the roots of Smilax glabra. The structures were elucidated by spectroscopic methods including 2DNMR techniques.
菝葜是一种著名的传统中药，临床上已用于预防钩端螺旋体病、治疗梅毒和急性细菌性痢疾等。其提取物具有抗肿瘤和抗动脉粥样硬化活性。从菝葜根中分离出一种新的异黄酮7,6'-二羟基3'-甲氧基异黄酮（1），以及两种已知化合物花旗松素（2）和落新妇苷（3）。通过包括二维核磁共振技术在内的光谱方法阐明了其结构。
