Wiessmann K J
Dtsch Med Wochenschr. 1975 Nov 28;100(48):2482-6. doi: 10.1055/s-0028-1106570.
Various aspects of pulmonary function were measured in eight patients with chronic bronchial obstructive disease, after five-month oral administration of a sustained-release aminophylline preparation (BY 108: Euphyllin retard). In addition to a sustained bronchodilator effect there was an improvement in static pulmonary volumes and a marked increase in forced expiratory volumes. The reduction in residual volume and of midcapacity is felt to be of particular importance in the prevention of pulmonary emphysema.
对八名慢性支气管阻塞性疾病患者口服一种缓释氨茶碱制剂(BY 108:长效氨茶碱)五个月后,测量了其肺功能的各个方面。除了持续的支气管扩张作用外,静态肺容量有所改善,用力呼气量显著增加。残余容积和中容量的减少被认为对预防肺气肿尤为重要。