Cheng Alan, Braunstein Joel B, Dennison Cheryl, Nass Caitlin, Blumenthal Roger S
The Ciccarone Center for Prevention of Heart Disease, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
Clin Cardiol. 2002 May;25(5):205-12. doi: 10.1002/clc.4950250503.
Cardiovascular disease (CVD) is the leading cause of death and disability in industrialized societies, due in large part to the lack of a comprehensive approach to control the risk factors for atherosclerosis. One strategy for reducing an individual's global CVD risk relies on a targeted approach that modifies each of the major independent risk factors prevalent in both symptomatic (secondary prevention) and asymptomatic (primary prevention) patients. These interventions include lipid lowering, smoking cessation, blood pressure control, glycemic control, regular exercise, and the use of various medications. This review offers an evidence-based strategy toward reducing an individual's global risk for CVD by addressing the modifiable, major independent risk factors.
心血管疾病(CVD)是工业化社会中导致死亡和残疾的主要原因,这在很大程度上归因于缺乏控制动脉粥样硬化风险因素的综合方法。降低个体整体心血管疾病风险的一种策略依赖于一种针对性方法,该方法可改变有症状(二级预防)和无症状(一级预防)患者中普遍存在的每一个主要独立风险因素。这些干预措施包括降脂、戒烟、血压控制、血糖控制、定期锻炼以及使用各种药物。本综述通过探讨可改变的主要独立风险因素,提供了一种基于证据的策略来降低个体患心血管疾病的整体风险。