Identification of a complete dfrA14 gene cassette integrated at a secondary site in a resistance plasmid of uropathogenic Escherichia coli from Nigeria.
作者信息
Ojo Kayode K, Kehrenberg Corinna, Schwarz Stefan, Odelola H Akin
出版信息
Antimicrob Agents Chemother. 2002 Jun;46(6):2054-5. doi: 10.1128/AAC.46.6.2054-2055.2002.
Abstract
摘要
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Resistance to trimethoprim and sulfonamides.对甲氧苄啶和磺胺类药物的耐药性。
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Gene cassettes: a new class of mobile element.基因盒：一类新型可移动元件。
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Secondary-sites for integration mediated by the Tn21 integrase.由Tn21整合酶介导的整合的二级位点。
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Plasmid evolution by acquisition of mobile gene cassettes: plasmid pIE723 contains the aadB gene cassette precisely inserted at a secondary site in the incQ plasmid RSF1010.通过获取移动基因盒实现质粒进化：质粒pIE723含有精确插入IncQ质粒RSF1010二级位点的aadB基因盒。
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Trimethoprim and sulfonamide resistance.甲氧苄啶和磺胺耐药性。
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Nucleotide sequence and genetic analysis of the type Ib trimethoprim-resistant, Tn4132-encoded dihydrofolate reductase.Ib型耐甲氧苄啶、Tn4132编码的二氢叶酸还原酶的核苷酸序列及遗传分析
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