Liu Richard, Seikaly Hadi, Jha Naresh
Division of Otolaryngology-Head and Neck Surgery, University of Alberta, Edmonston.
J Otolaryngol. 2002 Apr;31(2):76-9. doi: 10.2310/7070.2002.19035.
Xerostomia is the most common negative sequela after radiotherapy for head and neck cancer and results from destruction of normal salivary gland tissue by radiation. We hypothesized that transferring a single submandibular gland outside the radiation field to the submental region may preserve its function, thus preventing xerostomia and its consequences. This anatomic study was designed to evaluate different methods of submandibular gland transfer to the submental region. Eight submandibular glands were dissected in four fresh human cadavers. The anatomy and blood supply of the region were documented. Each gland was transferred to the submental region by either free microvascular transfer or based on retrograde flow through the distal facial vessels. Both methods of transfer resulted in complete relocation of the submandibular gland into the submental region.
口干症是头颈部癌放疗后最常见的负面后遗症，是由辐射破坏正常唾液腺组织所致。我们推测，将单个下颌下腺转移至放疗区域外的颏下区域可能会保留其功能，从而预防口干症及其后果。本解剖学研究旨在评估将下颌下腺转移至颏下区域的不同方法。在四具新鲜人类尸体上解剖了八个下颌下腺。记录了该区域的解剖结构和血液供应情况。每个腺体通过游离微血管转移或基于通过面远心端血管的逆行血流转移至颏下区域。两种转移方法均使下颌下腺完全重新定位到颏下区域。
